The traditional method of treating most human diseases is to direct a therapy against targets in the host patient, whereas conventional therapies against infectious diseases are directed against the pathogen. Unfortunately, the efficacy of pathogen-oriented therapies and their ability to combat emerging threats such as genetically engineered and non-traditional pathogens and toxins have been limited […]

In this presentation, some fundamentals of electrostatics in biology will be discussed with focus on the fact that most biological macromolecules including nucleic acids, carbohydrates, and proteins are negatively-charged. Electroneutrality requires cations to move toward the macromolecules where they both screen and bind to the negatively-charged groups. An important class of mathematical models of species-flux […]

Abstract: Remember smoking? What’s the new public health problem? In the US, we are currently entangled within three converging and intertwined complex problems: Cancer, Obesity, Aging. There are over 16 million cancer survivors living in the US as we speak. Over 50% of our society is overweight and/obese. Our society is aging and the age […]

Linear evolution equations, such as the heat equation, are commonly studied on finite spatial domains via initial-boundary value problems. In place of the boundary conditions, we consider “multipoint conditions”, where one specifies some linear combination of the solution and its derivative evaluated at internal points of the spatial domain, and “nonlocal” specification of the integral […]

Data is exploding at a faster rate than computer architectures can handle. For that reason, mathematical techniques to analyze large-scale data need be developed. Stochastic iterative algorithms have gained interest due to their low memory footprint and adaptability for large-scale data. In this talk, we will study the Randomized Kaczmarz algorithm for solving extremely large […]