BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Claremont Center for the Mathematical Sciences - ECPv6.15.17.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://colleges.claremont.edu/ccms
X-WR-CALDESC:Events for Claremont Center for the Mathematical Sciences
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Los_Angeles
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20200308T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20201101T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20210314T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20211107T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20220313T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20221106T090000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210215T150000
DTEND;TZID=America/Los_Angeles:20210215T160000
DTSTAMP:20260412T210308
CREATED:20210114T013414Z
LAST-MODIFIED:20210127T210557Z
UID:2120-1613401200-1613404800@colleges.claremont.edu
SUMMARY:Applied Math. Talk:  Modeling and Simulation of Ultrasound-mediated Drug Delivery to the Brain  by Peter Hinow\, University of Wisconsin\, Milwaukee
DESCRIPTION:We use a mathematical model to describe the delivery of a drug to a specific region of the brain. The drug is carried by liposomes that can release their cargo by application of focused ultrasound. Thereupon\, the drug is absorbed through the endothelial cells that line the brain capillaries and form the physiologically important blood-brain barrier. We present a compartmental model of a capillary that is able to capture the complex binding and transport processes the drug undergoes in the blood plasma and at the blood-brain barrier. We apply this model to the delivery of L-dopa\, (used to treat Parkinson’s disease) and doxorubicin (an anticancer agent). The goal is to optimize the delivery of drug while at the same time minimizing possible side effects of the ultrasound. In a second project\, we present a mathematical model for drug delivery through capillary networks with increasingly complex topologies with the goal to understand the scaling behavior of model predictions on a coarse-to-fine sequence of grids.
URL:https://colleges.claremont.edu/ccms/event/applied-math-talk-by-peter-hinow-university-of-wisconsin-milwaukee/
LOCATION:Zoom meeting\, United States
CATEGORIES:Applied Math Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210217T161500
DTEND;TZID=America/Los_Angeles:20210217T171500
DTSTAMP:20260412T210308
CREATED:20210116T021143Z
LAST-MODIFIED:20210204T000155Z
UID:2140-1613578500-1613582100@colleges.claremont.edu
SUMMARY:Dr. Homan Igehy
DESCRIPTION:Title: Quantitative Investment and Modern Portfolio Theory \nAbstract:\nInvestment strategies come in many flavors. Quantitative strategies incorporate or fully direct investment based on mathematical models. One of the cornerstones of investment is portfolio management\, and modern portfolio theory can serve as a basis for quantitative portfolio management. In this talk\, we will discuss quantitative investing and how modern portfolio theory can be incorporated into it. We’ll take an intuitive approach toward understanding modern portfolio theory and discuss how it can (at times\, spectacularly) go wrong. \nHoman Igehy is a managing director of D. E. Shaw & Co.\, L.P. and a member of the D. E. Shaw group’s Systematic Futures trading unit.  In that capacity\, Dr. Igehy contributes to the research and development of forecast models and the technical infrastructure supporting the unit’s research efforts.  He joined the D. E. Shaw group in 2003.  Dr. Igehy received a B.S. and Ph.D.\, each in computer science\, from Stanford University.
URL:https://colleges.claremont.edu/ccms/event/dr-homan-igehy/
LOCATION:Zoom
CATEGORIES:Colloquium
ORGANIZER;CN="Andrew Bernoff":MAILTO:ajb@hmc.edu
END:VEVENT
END:VCALENDAR