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DTSTART;TZID=America/Los_Angeles:20211101T161500
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SUMMARY:Applied Math Seminar — Selenne Bañuelos (Cal State University Channel Islands and Institute for Pure and Applied Mathematics\, UCLA)
DESCRIPTION:Title: Exploring Phage Treatment for Bacterial Infections with Mathematical Modeling \nAbstract: \nAntimicrobial resistance (AMR) is a serious threat to global health today. A renewed interest in phage therapy – the use of bacteriophages to treat pathogenic bacterial infections – has emerged given the spread of AMR and lack of new drug classes in the antibiotic pipeline. This talk will feature mathematical models from an ongoing research project that began in 2019 during the Collaborative Workshop for Women in Mathematical Biology at IPAM.  The first model considers the effect of phage-antibiotic combination therapy. We utilized this model to examine the role of the immune response in concert with phage-antibiotic combination therapy compounded with the effects of the immune system on the phages being used for treatment.  We will then discuss our current work as we collaborate with an experimental biologist.  This model investigates the bacteria-phage interaction in vitro.  We will discuss how our model has given insights into the challenges that arise from limited information in clinical trials\, and the delightful experience of how experimental biologists and applied mathematicians provide guidance to each other to move the project forward.
URL:https://colleges.claremont.edu/ccms/event/applied-math-seminar-selenne-banuelos-cal-state-university-channel-islands/
LOCATION:Emmy Noether Room\, Estella 1021\, Pomona College\,\, 610 N. College Ave.\, Claremont\, CA\, 91711\, United States
CATEGORIES:Applied Math Seminar
ORGANIZER;CN="Heather Zinn Brooks":MAILTO:hzinnbrooks@g.hmc.edu
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DTSTART;TZID=America/Los_Angeles:20211102T123000
DTEND;TZID=America/Los_Angeles:20211102T132000
DTSTAMP:20260406T152251
CREATED:20210826T052223Z
LAST-MODIFIED:20211025T185715Z
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SUMMARY:Counting points in discrete subgroups (Jeff Vaaler\, UT Austin)
DESCRIPTION:We consider the problem of comparing the number of discrete points that belong to a set with the measure (or volume) of the set\, under circumstances where we expect these two numbers to be approximately equal. We start with a locally compact\, abelian\, topological group G. We assume that G has a countably infinite\, torsion free\, discrete subgroup H. But to make the talk easier to follow we will mostly consider the case G = R^N and H = Z^N. If E ⊆ R^N is a subset there are many situations where one expects that the (finite\, positive) number Vol_N (E) is approximately equal to the cardinality |E ∩ Z^N |. We will sketch the proof of a general result that bounds the difference between these quantities. If k is an algebraic number field and k_A is the ring of adeles associated to k\, this general result is useful when G = k_A^N and H = k^N .
URL:https://colleges.claremont.edu/ccms/event/antc-seminar-jeff-vaaler-ut-austin/
LOCATION:On Zoom
CATEGORIES:Algebra / Number Theory / Combinatorics Seminar
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DTSTART;TZID=America/Los_Angeles:20211103T163000
DTEND;TZID=America/Los_Angeles:20211103T173000
DTSTAMP:20260406T152251
CREATED:20211028T230900Z
LAST-MODIFIED:20211028T231026Z
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SUMMARY:Topological descriptions of protein folding (Prof. Helen Wong)
DESCRIPTION:Title: Topological descriptions of protein folding\nSpeaker:  Prof. Helen Wong\, Department of Mathematical Sciences\, Claremont-McKenna College. \nAbstract: Knotting in proteins was once considered exceedingly rare. However\, systematic analyses of solved protein structures over the last two decades have demonstrated the existence of many deeply knotted proteins\, and researchers now hypothesize that the knotting presents some functional or evolutionary advantage for those proteins. Unfortunately\, little is known about how proteins fold into knotted configurations. In this talk\, we approach this problem from a theoretical point of view\, using techniques from the mathematical study of shape: Topology. We’ll discuss the topological tools currently used to quantify the complexity and depth of knotting in proteins\, and compare and contrast topological descriptions of proposed pathways for proteins to form knots. \n\nHelen Wong is an Associate Professor of Mathematics in the Department of Mathematical Sciences at Claremont McKenna College and an alumna of Pomona College. Her research is in low-dimensional quantum topology\, and applications of topology to molecular biology and quantum computation. She is particularly interested in the relationship between quantum invariants and related constructions (especially the Kauffman bracket skein algebra of a surface) and non-quantum invariants from topology and hyperbolic geometry.
URL:https://colleges.claremont.edu/ccms/event/topological-descriptions-of-protein-folding-prof-helen-wong/
LOCATION:Zoom
CATEGORIES:Colloquium
ORGANIZER;CN="Andrew Bernoff":MAILTO:ajb@hmc.edu
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