{"id":1181,"date":"2019-01-29T13:12:42","date_gmt":"2019-01-29T21:12:42","guid":{"rendered":"https:\/\/colleges.claremont.edu\/ccms\/?post_type=tribe_events&#038;p=1181"},"modified":"2019-04-18T23:40:38","modified_gmt":"2019-04-19T06:40:38","slug":"applied-math-seminar-given-by-helen-wong","status":"publish","type":"tribe_events","link":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/","title":{"rendered":"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC)"},"content":{"rendered":"<p>Knotting in proteins was once considered exceedingly rare.\u00a0 However, systematic analyses of solved protein structures over the last two decades have demonstrated the existence of many deeply knotted proteins, and researchers now hypothesize that the knotting presents some functional or evolutionary advantage for those proteins.<\/p>\n<p>&nbsp;<\/p>\n<p>Unfortunately, there is very little known (whether experimentally, through computer simulations, or theoretically) about how proteins fold into knotted configurations.\u00a0 <span class=\"contextualExtensionHighlight ms-font-color-themePrimary ms-border-color-themePrimary ident_844_938\" role=\"button\">In this\u00a0talk, we will discuss some of the theorized pathways from a topological point of view.<\/span>\u00a0 In particular, we propose a new theoretical pathway for protein knotting and determine its feasibility for certain families of\u00a0 proteins.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Knotting in proteins was once considered exceedingly rare.\u00a0 However, systematic analyses of solved protein structures over the last two decades have demonstrated the existence of many deeply knotted proteins, and [&hellip;]<\/p>\n","protected":false},"author":58,"featured_media":0,"template":"","meta":{"_acf_changed":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","_tec_slr_enabled":"","_tec_slr_layout":""},"tags":[],"tribe_events_cat":[15],"class_list":["post-1181","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-applied-math-seminar","cat_applied-math-seminar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC) - Claremont Center for the Mathematical Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC) - Claremont Center for the Mathematical Sciences\" \/>\n<meta property=\"og:description\" content=\"Knotting in proteins was once considered exceedingly rare.\u00a0 However, systematic analyses of solved protein structures over the last two decades have demonstrated the existence of many deeply knotted proteins, and [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/\" \/>\n<meta property=\"og:site_name\" content=\"Claremont Center for the Mathematical Sciences\" \/>\n<meta property=\"article:modified_time\" content=\"2019-04-19T06:40:38+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/\",\"url\":\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/\",\"name\":\"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC) - Claremont Center for the Mathematical Sciences\",\"isPartOf\":{\"@id\":\"https:\/\/colleges.claremont.edu\/ccms\/#website\"},\"datePublished\":\"2019-01-29T21:12:42+00:00\",\"dateModified\":\"2019-04-19T06:40:38+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/colleges.claremont.edu\/ccms\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Events\",\"item\":\"https:\/\/colleges.claremont.edu\/ccms\/events\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/colleges.claremont.edu\/ccms\/#website\",\"url\":\"https:\/\/colleges.claremont.edu\/ccms\/\",\"name\":\"Claremont Center for the Mathematical Sciences\",\"description\":\"Proudly Serving the Math Community at the Claremont Colleges Since 2007\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/colleges.claremont.edu\/ccms\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC) - Claremont Center for the Mathematical Sciences","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/","og_locale":"en_US","og_type":"article","og_title":"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC) - Claremont Center for the Mathematical Sciences","og_description":"Knotting in proteins was once considered exceedingly rare.\u00a0 However, systematic analyses of solved protein structures over the last two decades have demonstrated the existence of many deeply knotted proteins, and [&hellip;]","og_url":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/","og_site_name":"Claremont Center for the Mathematical Sciences","article_modified_time":"2019-04-19T06:40:38+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/","url":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/","name":"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC) - Claremont Center for the Mathematical Sciences","isPartOf":{"@id":"https:\/\/colleges.claremont.edu\/ccms\/#website"},"datePublished":"2019-01-29T21:12:42+00:00","dateModified":"2019-04-19T06:40:38+00:00","breadcrumb":{"@id":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/colleges.claremont.edu\/ccms\/event\/applied-math-seminar-given-by-helen-wong\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/colleges.claremont.edu\/ccms\/"},{"@type":"ListItem","position":2,"name":"Events","item":"https:\/\/colleges.claremont.edu\/ccms\/events\/"},{"@type":"ListItem","position":3,"name":"Applied math seminar: Topological descriptions of protein folding (Helen Wong, CMC)"}]},{"@type":"WebSite","@id":"https:\/\/colleges.claremont.edu\/ccms\/#website","url":"https:\/\/colleges.claremont.edu\/ccms\/","name":"Claremont Center for the Mathematical Sciences","description":"Proudly Serving the Math Community at the Claremont Colleges Since 2007","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/colleges.claremont.edu\/ccms\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"ticketed":false,"_links":{"self":[{"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/tribe_events\/1181","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/tribe_events"}],"about":[{"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/users\/58"}],"version-history":[{"count":0,"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/tribe_events\/1181\/revisions"}],"wp:attachment":[{"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/media?parent=1181"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/tags?post=1181"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/colleges.claremont.edu\/ccms\/wp-json\/wp\/v2\/tribe_events_cat?post=1181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}