We use a mathematical model to describe the delivery of a drug to a specific region of the brain. The drug is carried by liposomes that can release their cargo by application of focused ultrasound. Thereupon, the drug is absorbed through the endothelial cells that line the brain capillaries and form the physiologically important blood-brain […]
Title: Quantitative Investment and Modern Portfolio Theory Abstract: Investment strategies come in many flavors. Quantitative strategies incorporate or fully direct investment based on mathematical models. One of the cornerstones of investment is portfolio management, and modern portfolio theory can serve as a basis for quantitative portfolio management. In this talk, we will discuss quantitative investing […]
Abstract: The identification of potential super-spreader nodes within a network is a critical part of the study and analysis of real-world networks. Motivated by a new interpretation of the “shortest path” between two nodes, this talk will explore the properties of the recently proposed measure, the heatmap centrality, by comparing the farness of a node […]
Title: Using Topology to Measure Shape in Data Abstract: Data of various kinds is being collected at an enormous rate, and in many different forms. Often, the data are equipped with a notion of distance that reflects similarity in some sense. Using this similarity measure, certain topological features--e.g. the number of connected components, loops, and […]
Abstract: The Landau-de Gennes theory is a type of continuum theory that describes nematic liquid crystal configurations in the framework of the Q-tensor order parameter. In the free energy, there is a singular bulk potential which is considered as a natural enforcement of a physical constraint on the eigenvalues of symmetric, traceless Q-tensors. In this […]
Title: Spectral gap in random regular graphs and hypergraphs Abstract: Random graphs and hypergraphs have been used for decades to model large-scale networks, from biological, to electrical, and to social. Various random graphs (and their not-so-random properties) have been connected to algorithms solving problems from community detection to matrix completion, coding theory, and various other […]
Abstract The COVID-19 pandemic illustrates the importance of treatment-related decision making in populations. This article considers the case where the transmission rate of the disease as well as the efficiency of treatments is subject to uncertainty. We consider two different regimes, or submodels, of the stochastic SIR model, where the population consists of three groups: […]
TBA
Title: Finding soap films in non-Euclidean geometry Abstract: In many computer graphics applications we approximate a smooth surface with one made up of tiny triangles. A common problem is to determine which way to move the vertices (the corners of the triangles), so that the total surface area decreases. If the boundary of the surface […]
Abstract: I will overview the following different wave phenomena in integrable nonlinear wave equations: (1) universal patterns in the dynamics of fluxon condensates in the semi-classical limit; (2) modulational instability of periodic travelling waves; (3) rogue waves on the background of periodic and double-periodic waves. Main examples include the sine-Gordon equation, the nonlinear […]
Title: Our muscles aren't one-dimensional fibres. Abstract: Skeletal muscles possess rather amazing mechanical properties. They possess an intricate structure, and behave nonlinearly in response to mechanical stresses. In the 1910s, A.V. Hill observed muscles heat when they contract, but not when they relax. Based on experiments on frogs he posited a mathematical description of skeletal […]
Abstract: The system of shallow water equations and related models are widely used in oceanography to model hazardous phenomena such as tsunamis and storm surges. Unfortunately, the inherent uncertainties in the system will inevitably damage the credibility of decision-making based on the deterministic model. The stochastic Galerkin (SG) method seeks a solution by applying the […]
