Title: A common pathway to cancer: oncogenic mutations abolish p53 oscillations. Abstract: The tumor suppressor p53 oscillates in response to DNA double-strand breaks, a behavior that has been suggested to be essential to its anti-cancer function. Nearly all human cancers have genetic alterations in the p53 pathway; a number of these alterations have been shown to […]
Title: PLSS: A Projected Linear Systems Solver (joint work with Michael Saunders) Abstract: Iteratively solving linear systems has proven to be useful for many large applications. Projection methods use sketching matrices (possibly randomized) to generate a sequence of small projected subproblems, but even the smaller systems can be costly. We develop a method in which […]
Title: Modeling size distributions and collisions in cloud microphysics Abstract: Feedbacks between a warming atmosphere, emission of aerosols, and clouds and precipitation are one of the most difficult aspects for climate models to accurately capture. While these models operate at resolutions of tens or hundreds of kilometers, many of the physics that determine how and […]
Title: Towards Understanding the Success of First Order Methods in Training Mildly Overparameterized Networks Abstract: For most problems of interest the loss landscape of a neural network is non-convex and […]
Title: Understanding SARS-CoV-2 viral rebounds with and without treatments. Abstract: In most instances, the characteristics of SARS-CoV-2 mirror the patterns of an acute infection, with viral load rapidly peaking around 5 days post-infection and subsequently clearing within 2 weeks. However, some individuals show signs of viral recrudescence of up to 10000 viral RNA copies/mL shortly […]
Title: The Hartman-Watson distribution: numerical evaluation and applications in mathematical finance Abstract: The Hartman-Watson distribution appears in several problems of applied probability and financial mathematics. Most notably, it determines the […]
Title: Recalibration of Predicted Probabilities Using the "Logit Shift": Why Does It Work, and When Can It Be Expected to Work Well? Abstract: In the context of election analysis, researchers […]
Title Control algorithms for unmanned underwater vehicles: new approaches based on Hamilton-Jacobi equations and reinforcement learning. Abstract Unmanned underwater vehicles (UUVs) are defined by their ability to operate without direct […]
During this student-centered Applied Math Seminar, there will be discussion and presentations about upcoming courses offered in applied mathematics, to help students make their enrollment choices for Spring 2024 and […]
Title: On the Composition of Classical Mechanical Systems Abstract: Compositionality is a basic principle for understanding the physical world. The underlying idea is to study a system by studying the ways in which the components of the system compose to form the system. Category theory is an area in mathematics that is particularly well-suited for […]
Title: Existence and multiplicity of solutions for a cooperative elliptic system using Morse theory This is joint work with Leandro Recova (Cal Poly Pomona) Abstract
Title: Tropical Linear Series Abstract: In this talk I'll attempt to give a friendly and example-driven introduction to the theory of linear series on tropical curves. While in some respects mirroring […]
